Glibenclamide / Metformin Hydrochloride 2.5 mg / 500 mg Tablets

? Why is it used?

• ✅ Lowers blood sugar levels in Type 2 Diabetes (non-insulin-dependent) as an adjunct to a healthy diet and exercise.

? Do not take this medication if you:

• ❌ Are allergic to Glibenclamide, Metformin, sulfonylureas, sulfonamides, or any other ingredient in this medication.
• ❌ Have Type 1 Diabetes.
• ❌ Suffer from diabetic ketoacidosis.
• ❌ Have severe liver or kidney problems.
• ❌ Are dehydrated, have a severe infection, or heart failure.
• ❌ Drink excessive alcohol or take Bosentan for high blood pressure.

⚠️ Precautions

• ? Inform your doctor if you have:
  • Liver or kidney issues.
  • Heart disease.
  • Recovering from injury, surgery, or an infection.
  • G6PD deficiency.
  • May cause lactic acidosis, especially with kidney problems. Symptoms include abdominal pain, vomiting, muscle cramps, fatigue, and difficulty breathing.
  • May cause hypoglycemia (low blood sugar) if you skip meals, over-exercise, or drink alcohol.

⚠️ Potential Side Effects

• ? Severe allergic reactions (difficulty breathing, facial swelling).
• ? Hypoglycemia (nausea, trembling, dizziness).
• ? Liver problems.
• ? Lactic acidosis.

? Other medications that may interact with Glibenclamide / Metformin Hydrochloride

• ? Other diabetes medications.
• ? Blood pressure medications.
• ? Anticoagulants like warfarin.
• ? Corticosteroids, certain asthma and infection medications.

? How to take Glibenclamide / Metformin Hydrochloride

• ? For adults only.
• ?️ Take with food.
• ? Usual starting dose: Glibenclamide 1.25 - 2.5 mg / Metformin 500 - 1000 mg, once or twice daily.

?️ How to store the medication

• ?️ Store at room temperature (20-25°C).
• ❌ Do not use after the expiry date.