? What is Metformin XR Extended Release and What Is It Used For?

Metformin XR Extended Release tablets are oral medications used to manage type 2 diabetes by lowering blood sugar levels.
They help control blood glucose and improve the body’s ability to use insulin effectively.
This medication is often combined with changes in diet and exercise.
It may also be used for other purposes; ask your healthcare provider or pharmacist if you have any questions.

? How to Use Metformin XR

• There is no fixed dosage for controlling high blood sugar with Metformin XR.
• The dosage should be individualized based on effectiveness and tolerance, without exceeding the recommended maximum daily dose.
• The maximum recommended daily dose for adults is 2000 mg.
• Metformin XR is generally given once daily with the evening meal.
• Start with a low dose, gradually increasing to minimize gastrointestinal side effects and find the lowest dose needed to control blood sugar effectively.

? Recommended Dosage for Adults

• The usual starting dose is 500 mg once daily with the evening meal.
• Increase the dose by 500 mg weekly, up to a maximum of 2000 mg once daily with the evening meal.
• If blood sugar control is not achieved with 2000 mg once daily, consider trying 1000 mg twice daily.
• If higher doses of metformin are required, the total daily dose can go up to 2550 mg in divided doses.

⚠ Warnings and Precautions

• Risk of Lactic Acidosis: Metformin hydrochloride may cause a rare but serious side effect called lactic acidosis, especially in patients with kidney problems or uncontrolled diabetes.
  Discontinue Metformin and contact your doctor immediately if you experience symptoms of lactic acidosis, such as:
  • Vomiting, stomach pain, muscle cramps, severe fatigue, difficulty breathing, low body temperature, and irregular heartbeat.
• Risk of Hypoglycemia: When taking Metformin with other diabetes medications, hypoglycemia may occur.
  If you experience symptoms of hypoglycemia such as weakness, dizziness, increased sweating, rapid heartbeat, or vision problems, consuming something with sugar should help.

? Possible Side Effects of Metformin Hydrochloride

• Lactic acidosis
• Gastrointestinal issues such as nausea, vomiting, diarrhea, stomach pain, and loss of appetite
• Changes in taste

? Other Medicines and Metformin Hydrochloride

Inform your doctor if you are taking or have recently taken any other medications, including:

• Diuretics
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Certain high blood pressure medications
• Beta-2 agonists like salbutamol (for asthma)
• Corticosteroids
• Other diabetes medications

? Ingredients

This medication is available in various concentrations from multiple manufacturers:

• 500 mg: Each extended-release tablet contains 500 mg of metformin hydrochloride.
• 750 mg: Each extended-release tablet contains 750 mg of metformin hydrochloride.
• 1000 mg: Each extended-release tablet contains 1000 mg of metformin hydrochloride.